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With its chill vibe, ACME Hotel Chicago unites an artful eye for whimsical style and a penchant for high-tech toys for both work and play, making it the city's most approachable lifestyle hotel. Conde Nast 2021 Award Winner. Voted #10 for top hotels in the Chicago area. ACME is Located just off Michigan Avenue in the vibrant River North neighborhood of Chicago. Located just steps from the Magnificent Mile. ACME is all about self-expression and its tagline, DO YOUR THING is a celebration of guests' individuality. The vibrant lobby bar, The Berkshire Room, is an imaginative cocktail destination for locals, and the second floor Bodega offers a chill alternative with custom bottled drinks. Guests can even book the Bunny Slope, Chicago's talked-about hot tub bar to hit the nightlife scene. ACME Hotel features 130 imaginatively decorated rooms and suites equipped with Amazon Alexas to answer to every guest whim, high fidelity Bowers and Wilkens Zepplin players, and ultra-fast, free Wi-Fi throughout. To arrange your stay at this one-of-a-kind Chicago hotel, please see our rates and availability for the ACME Hotel.