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Holiday Inn Express Greenville NC is ready to welcome summer travelers with an inviting stay. From sunny mornings to Carolina nights, our hotel delivers comfort, style, and convenience, making it a top choice for leisure and business guests visiting Greenville.Located in the heart of the Medical District, we are just steps from ECU Medical Center, Leo Jenkins Cancer Center, East Carolina Heart Institute, Brody School of Medicine, and East Carolina Dental School. Guests appreciate our modern spaces, thoughtful design, and relaxing atmosphere while attending appointments, training, or supporting loved ones.Only minutes from East Carolina University and its athletic venues, including Dowdy-Ficklen Stadium, Clark-LeClair Stadium, and Minges Coliseum, our location is ideal for summer camps, tournaments, campus programs, and local events. Outdoor enthusiasts enjoy Elm Street Park, while business travelers benefit from access to Thermo-Fisher Scientific, Catalent, Hyster-Yale, Grady-White Boats, Attindas, and Pitt Community College.Start each day with a complimentary hot breakfast buffet and stay connected with high-speed internet. Additional amenities include a meeting room, full Business Center, and the opportunity to earn IHG One Rewards points on every stay.Just three miles from Pitt-Greenville Airport with a complimentary shuttle, we make summer travel easy so you can Stay Smart and enjoy Greenville NC all season long.