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Houston Hotel near Texas Medical Center and NRG Stadium. Welcome to our Holiday Inn Express & Suites Houston S - Medical Ctr Area hotel. Our location near Texas Medical Center and NRG Stadium and Arena is perfect for business and leisure travelers alike. We offer a free shuttle to and from the Medical Center. Our hotel is a mile away from NRG Stadium and Arena, which makes it a very convenient place to stay if you are planning to attend a Texans Football game, a concert, a show, or an event like the annual Houston Livestock show and Rodeo. While in Houston, be sure to explore the Museum District, Houston Zoo, and Hermann Park, just minutes from our hotel. A short drive will take you to the NASA Johnson Space Center or the Kemah Boardwalk on the Gulf of Mexico. In need of retail therapy? Find everything and more at The Galleria. For a more unique shopping experience, check out Rice Village, one of Houston’s hidden gems; offering boutique shopping, exquisite restaurants, and trendy nightlife options. Several amenities await you at our Texas Medical Center hotel. Start your day with free, hot breakfast, and get a workout in at our Fitness Center. Stay productive at our Business Center, and enjoy free Wi-Fi throughout the hotel. If you need to host an event, our large, dividable meeting room is ideal and can hold up to 66 people. We look forward to seeing you soon at our hotel near Houston Medical Center.