We loved our stay at Hotel del Corso. The staff were welcoming and helpful in providing maps and tours of the city. They even helped us get our luggage up the stairs. The rooms were charming and comfortable and had all the amenities we needed (wifi, hair dryer, coffee maker, and welcome snacks).
With a stay at Corso in Florence (Duomo), you'll be within a 5-minute walk of Piazza del Duomo and Piazza della Signoria.